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WebJun 2, 2024 · Methods: Paired blood and tumor biopsy samples were collected from a patient with hepatocellular carcinoma before and after treatment with GNOS-PV02 (DNA neoantigen targeted vaccine) + plasmid IL-12 + pembrolizumab. Treatment resulted in a partial response with a decrease in tumor size of 44% by RECIST (168 mm to 94 mm). WebMar 18, 2024 · The availability and low cost of high-throughput sequencing technologies have led to the identification of numerous tumor neoantigens. The in-depth study of immunological mechanisms and various new vaccine platforms have extensively promoted cancer vaccines research. ... (GNOS-PV02) encodes up to 40 neoantigens, including all … WebThe IPV-HP2 High Precision Leveling Valve provides re-leveling accuracy to better than ±0.002 in. (0.05 mm) compared to our standard precision leveling valves with ±0.010 inch … cscsw check balance