Nrf1 chip
WebThe set of ChIP-Seq-based NRF1 target genes included known NRF1 targets such as EIF2S1, EIF2S2, CYCS, FMR1, FXR2, E2F6, CD47, and TOMM34. By pathway analysis, the molecules located in the core pathways related to mitochondrial respiratory function were determined to be highly enriched in NRF1 target genes. WebChIP - Anti-NRF1 antibody [EPR5554(N)] - BSA and Azide free (ab221792) Chromatin was prepared from NIH/3T3 treated with MG-132(2uM 16h) cells according to the Abcam Dual X-ChIP protocol*. Cells were fixed with EGS for 30 minutes, then formaldehyde for 10 minutes.
Nrf1 chip
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Web20 aug. 2024 · To identify network-based pathways involved in the susceptibility to the ER/PR −ve HER2 +ve breast cancer subtype, the NRF1 transcriptional regulatory genome-wide landscape was analyzed using the approach consisting of a systematic integration of ChIP DNA-seq, RNA-Microarray, NRF1 protein-DNA motif binding, signal pathway … Webusing the approach consisting of a systematic integration of ChIP DNA-seq, RNA-Microarray, NRF1 protein-DNA motif binding, signal pathway analysis, and Bayesian machine learning. Our findings show that a high percentage of known HER2+ breast cancer susceptibility genes, including EGFR, IGFR, and E2F1, are under transcriptional control …
Web21 mrt. 2024 · NRF1 (Nuclear Respiratory Factor 1) is a Protein Coding gene. Diseases associated with NRF1 include Oncocytoma and Skin Carcinoma In Situ . Among its related pathways are Transcriptional activation of mitochondrial biogenesis and PPARA activates gene expression . Web12 aug. 2024 · The NRF1 ChIP-seq data from the ENCODE project confirms the binding of NRF1 to ATG5 and ATG7 promoter regions in 4 different cancer cells (HepG2, K562, SK …
WebChIP - Anti-NRF1 antibody [EPR5554(N)] - BSA and Azide free (ab221792) Chromatin was prepared from NIH/3T3 treated with MG-132(2uM 16h) cells according to the Abcam … Web22 okt. 2015 · Our integrative analyses of EglN2 ChIP-Seq and gene expression profiling under hypoxic conditions unveil a unique NRF1 motif enrichment in EglN2-upregulated genes. Mechanistically, by forming an activator complex with PGC1α and NRF1 on chromatin, EglN2 promotes FDXR gene expression and regulates mitochondrial function …
Web22 okt. 2015 · ses of EglN2 and NRF1 ChIP-Seq data, as well as EglN2-mediated. differential mRNA expression, identify genes potentially involved in. mitochondrial functions. Among these genes, FDXR is the most.
Web[13]. Indeed, NRF1 binding elements have been identified in genes involved in cellular growth, metabolic energy produc-tion, protein translation and DNA replication/repair [13]. ChIP-on-chip analysis of human T98G glioblastoma-derived cells showed that NRF1 binds to ~691 genes encoding pro-teins regulating cellular growth, DNA replication, DNA re- balam pcWebChIP was performed using K562 cells, the Diagenode monoclonal antibody against NRF1 (Cat. No. C15200013) and optimized PCR primer sets for qPCR. ChIP was performed … balam pecheWebNuclear respiratory factor 1 (NRF1) was identified as a transcription activator for the gene encoding cytochrome c (1). It was later found to play a role in the nuclear control of … balam peintreWebNRF1 (UniProt/Swiss-Prot entry Q16656) is a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes … ari50701WebAll lanes : Anti-NRF1 antibody [EPR5554(N)] - ChIP Grade (ab175932) at 1/1000 dilution (unpurified) Lane 1 : MCF-7 cell lysate Lane 2 : Hela cell … balampetWeb25 jul. 2024 · Here, we present emerging data supporting novel roles of NRF1 in cancer development and progression through its interplay with the transcription factors E2F4 and MYC. To identify common human NRF1, E2F4 and MYC target genes, we analyzed the Encyclopedia of DNA Elements (ENCODE) NRF1 ChIP-Seq data. balam pardesia bhojpuriWeb11 jan. 2024 · Second, our comprehensive genome-wide ChIP-seq studies for Mll4 and Nrf1 uncovered that Mll4 partners mainly with Nrf1 to activate the expression of GHRH … ari 504